产品货号：
Z17062
中文名称：
GGA1抗体
英文名称：
Anti-GGA1 Antibody
产品规格：
100μg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-GGA1 Antibody |
| 指标别名 | GGA1 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,WB |
| 基因名称 | GGA1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This affinity-purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near amino acids 330-360 of Human GGA-1. |
| 计算分子量 | 62kDa |
| 成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,0.01% (w/v) Sodium Azide |
| 纯化方式 | This affinity purified antibody is directed against human GGA1 protein.The product was affinity purified from monospecific antiserum by immunoaffinity purification.A BLAST analysis was used to suggest reactivity with this protein from human based on 100% homology for the immunogen sequence.Cross-reactivity may occur with GGA1 from bovine (87% homology),mouse (82% homology) and rat (76% homology) sources.The immunizing sequence is present only in isoform 1 of this protein,therefore cross-reactivity with splice variants is not expected.Cross-reactivity with GGA1 homologues from other sources has not been determined. |
| 浓度 | 1.35mg/mL by UV absorbance at 280nm |
| 产品形态 | 溶液 |
| 保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
| 背景资料 | GGA1 (also known as ADP-ribosylation factor binding protein,Golgi-localized,gamma ear-containing,ARF-binding protein 1,Gamma-adaptin related protein 1) plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes.This protein mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif.GGA1 is a monomeric protein that interacts with NECAP1,GGA2 and GGA3 as well as RABEP1,RABGEF1 and type-I membrane proteins SORT1,SORL1,LRP3,M6PR/CD-MPR,IGF2R/CI-MPR and BACE1.GGA1 is a ubiquitously membrane-associated protein that is localized to TGN and endosomes.Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Uniprot ID | Q9UJY5 |
| 推荐稀释比 | ELISA:1:10,000 - 1:50,000 IP:1:100 WB:1:500 - 1:3,000 |
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